We find that the mental health burden for adolescents living with HIV is high, contributing to low quality of life and challenges with adherence to antiretroviral therapy. We provide a detailed overview of mental health provision and collate evidence for future approaches. In this Series paper, we review systematic reviews, randomised trials, and cohort studies of adolescents living with and affected by HIV. More than 90% of adolescents living with HIV reside in sub-Saharan Africa, where their mental health is set against a background of poverty, familial stress, service gaps, and an HIV epidemic that is now intertwined with the COVID-19 pandemic. 16 Department of Information Systems, University of the Western Cape, Cape Town, South Africa.Īdolescents are a crucial generation, with the potential to bring future social and economic success for themselves and their countries.15 Institute for Life Course Health Research, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa School of Nursing and Midwifery, Queens University, Belfast, UK.14 Teen Advisory Group, University of Cape Town, Cape Town, South Africa.13 Institute for Life Course Health Research, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.11 Centre for Rural Health, University of KwaZulu-Natal, Durban, South Africa.10 Global HIV, Hepatitis and Sexually Transmitted Infections Programmes, World Health Organization, Geneva, Switzerland.9 Highly Vulnerable Children Research Center, Cape Town, South Africa Tulane University School of Public Health, New Orleans, LA, USA.8 Agency for Research and Development Initiative, Juba, South Sudan.7 Department of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.6 Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria.5 HIV Center for Clinical and Behavioral Studies, Department of Psychiatry, New York State Psychiatric Institute, New York, NY, USA Columbia University Irving Medical Center, New York, NY, USA.4 Centre for Social Science Research, University of Cape Town, Cape Town, South Africa School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.3 Department of Social Policy and Intervention, University of Oxford, Oxford, UK Centre for Social Science Research, University of Cape Town, Cape Town, South Africa.Electronic address: 2 Institute of Global Health, University College London, London, UK. 1 Department of Social Policy and Intervention, University of Oxford, Oxford, UK Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
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